Digital transformation means embracing digital technologies and with that transforming business models, socio-economic structures, legal and policy measures, organizational patterns and even cultural barriers. Nearly every CEO and CIO see digital transformation on top of their agenda in 2016. At Microsoft, we strongly believe that every organization and every institution will become a digital company in the next few years. The digital transformation has a profound impact on four pillars of every organization. Firstly it changes the way we engage with our customers, as more and more interactions the customer and the firm happen the digital space. Secondly, the digital transformation empowers employees to take the right decision and to be agile in responding to customer needs, based on insights. Thirdly, operations and business process can streamlined and controlled in real time, resulting in superior efficiency for the ones most innovative. Last but not least, the digital transformation changes the products, the services and the whole business models. Start-ups have a superior advantage compared to the traditional business, as they do not undergo digital transformation – they are born in the cloud! Let’s discover how start-ups can use this strategic advantage, what technologies can be useful and what Microsoft programs are available to start-ups.